Publikationen zum Thema Spiroergometrie
In der Tabelle finden Sie eine umfangreiche Übersicht über nationale und internationale Publikationen/Artikel, in denen CORTEX-Systeme vorgestellt und verwendet werden.
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- Nr Titel Autoren/Institut Segement Produkt
- 2015-036 Right Ventricular Mass is Associated with Exercise Capacity in Adults with Repaired Tetralogy of Fal O’Meagher, Shamus; Seneviratne, Martin; Skilton, M
Produktbereich: Veröffentlichung: ArticleSprache: EngishVerlag/Herausgeber: Pediatric Cardiology, August 2015, Vol. 36 Issue: Number 6 p1225-1231, 7p
Abstract:
The relationship between exercise capacity and right ventricular (RV) structure and function in adult repaired tetralogy ofFallot (TOF) is poorly understood. We therefore aimed to examine the relationships between cardiac MRI and cardiopulmonary exercise test
The relationship between exercise capacity and right ventricular (RV) structure and function in adult repaired tetralogy ofFallot (TOF) is poorly understood. We therefore aimed to examine the relationships between cardiac MRI and cardiopulmonary exercise test
variables in adult repaired TOF patients. In particular, we sought todetermine the role of RV mass in determining exercise capacity. Eighty-two adult repaired TOF patients (age at evaluation 26 ± 10 years; mean age at repair 2.5 ± 2.8 years; 23.3 ± 7.9 years
since repair; 53 males) (including nine patients with tetralogy-type pulmonary atresia with ventricular septal defect) were prospectively recruited to undergo cardiac MRI and cardiopulmonary exercise testing.
As expected, these repaired TOF patients had RV dilatation (indexed RV end-diastolic volume: 153 ± 43.9 mL/m2), moderate–severe pulmonary regurgitation (pulmonary regurgitant fraction: 33 ± 14 %) and preserved left (LV ejection fraction: 59 ± 8 %) and RV systolic function (RV ejection fraction: 51 ± 7 %). Exercise capacity was near-normal (peak work: 88 ± 17 % predicted; peak oxygen consumption: 84 ± 17 % predicted). Peak work exhibited a significant positive correlation with RV mass in univariate analysis (r= 0.45, p< 0.001) and (independent of other cardiac MRI variables) in multivariate analyses. For each 10 g higher RV mass, peak work was 8 W higher. Peak work exhibits a significant positive correlation with RV mass, independent of other cardiac MRI variables. RV mass measured on cardiac MRI may provide a novel marker of clinical progress in adult patients with repaired TOF.
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